ACR RA guidelines: ‘Maximize’ methotrexate use prior to DMARDs, avoid glucocorticoids

Sumary of ACR RA guidelines: ‘Maximize’ methotrexate use prior to DMARDs, avoid glucocorticoids:

  • The American College of Rheumatology has released its updated treatment guidelines for rheumatoid arthritis, with a strong emphasis on the use of methotrexate before adding or switching to DMARDs, according to the lead author..
  • “The key messages are to maximize use of methotrexate prior to adding or switching to disease-modifying antirheumatic drugs,”.
  • “The key messages are to maximize use of methotrexate prior to adding or switching disease modifying antirheumatic drugs,”.
  • The 2021 guidelines for RA include a total of 44 recommendations, including seven strong and 37 conditional items..
  • According to Fraenkel, the ACR continues to strongly recommend targeted treatment for patients without previous exposure to biologic or targeted synthetic DMARDs;.
  • There are also, for the first time, recommendations that address patients with nontuberculous mycobacterial lung disease..
  • “Another key takeaway is recommendations to try to avoid glucocorticoids whenever possible, including low-dose glucocorticoids,”.
  • The final voting panel, which included 13 clinicians and two patients, then assessed the evidence reports and patient perspectives before casting their ballots on each recommendation….

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