Sumary of Air pollution linked to myocardial fibrosis in patients with CKD:
- Nine million of total deaths are directly attributable to environmental pollution,” Hafsa Tariq, MD, from University Hospitals Cleveland Medical Center, Case Western Reserve University, said.
- Researchers analyzed 1,019 patients from the Systolic Blood Pressure Intervention Trial (SPRINT) with Galectin 3 levels available at baseline.
- The correlation between air pollution and Galectin 3 at baseline and 2 years was determined by multivariable linear regression models adjusted for age, sex, race, eGFR, Framingham risk score, BMI and randomization assignment.
- Multivariable models revealed no correlation between PM2.5 and Galectin 3 at baseline or longitudinal change, however there was a statistically significant change observed in the subgroup of participants with CKD (n=201).