Air pollution linked to myocardial fibrosis in patients with CKD

air pollution linked to myocardial fibrosis in patients with ckd

Sumary of Air pollution linked to myocardial fibrosis in patients with CKD:

  • Nine million of total deaths are directly attributable to environmental pollution,” Hafsa Tariq, MD, from University Hospitals Cleveland Medical Center, Case Western Reserve University, said.
  • Researchers analyzed 1,019 patients from the Systolic Blood Pressure Intervention Trial (SPRINT) with Galectin 3 levels available at baseline.
  • The correlation between air pollution and Galectin 3 at baseline and 2 years was determined by multivariable linear regression models adjusted for age, sex, race, eGFR, Framingham risk score, BMI and randomization assignment.
  • Multivariable models revealed no correlation between PM2.5 and Galectin 3 at baseline or longitudinal change, however there was a statistically significant change observed in the subgroup of participants with CKD (n=201).

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