Sumary of Alzheimer’s research gives hope to patients as scientists suggest jab can reverse dementia in mice :
- Scientists developing a vaccine against Alzheimer’s disease say they are ‘hugely excited’ by findings suggesting it can reverse dementia in mice.
- The pioneering therapy, costing only £15 a dose, works by preventing the formation of harmful deposits of protein in the brain linked to memory loss.
- Dementia affects about 850,000 people in the UK and is currently incurable, but experts said the new vaccine could enter clinical trials in humans within two years.
- Scientists are ‘hugely excited’ about a vaccine that may reverse dementia.
- The disease affects about 850,000 people in the UK and is currently incurableAlzheimer’s disease is thought to be caused when naturally occurring proteins called amyloid beta clump together to form plaques in the brain.
- These plaques occur when separate amyloid beta protein molecules become shortened or ‘truncated’, then join together to form clusters that interfere with the functioning of brain cells.
- But scientists have identified an antibody – called TAP01-04 – which binds to the shortened toxic form of amyloid beta, preventing the molecules clumping together to form plaques.
- ‘ Co-author Professor Thomas Bayer, from the University Medical Centre Gottingen in Germany, said: ‘In clinical trials, none of the potential treatments which dissolve amyloid plaques in the brain have shown much success in terms of reducing Alzheimer’s symptoms.