Antipsychotic drug could reduce dementia-related psychosis symptoms

Sumary of Antipsychotic drug could reduce dementia-related psychosis symptoms:

  • © iStock/designer491 The benefits of an antipsychotic treatment for people with dementia-related psychosis have been demonstrated in a new study.
  • Researchers discovered significant sustained benefits of the treatment, when compared to those put onto a placebo.
  • Pimavanserin blocks serotonin 5HT2A receptors and does not interact with the dopamine receptors.
  • In the study of 392 people with dementia-related psychosis, researchers administered pimavanserin to all participants for 12 weeks.
  • Of the 351 participants, 217 (61.8%) had a sustained initial treatment benefit – with 112 of these then assigned to the placebo and 105 to pimavanserin.
  • This shows that pimvanserin more than halved the relapse rate and significantly improved the sustained benefit.

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