Sumary of Antipsychotic drug could reduce dementia-related psychosis symptoms:
- © iStock/designer491 The benefits of an antipsychotic treatment for people with dementia-related psychosis have been demonstrated in a new study.
- Researchers discovered significant sustained benefits of the treatment, when compared to those put onto a placebo.
- Pimavanserin blocks serotonin 5HT2A receptors and does not interact with the dopamine receptors.
- In the study of 392 people with dementia-related psychosis, researchers administered pimavanserin to all participants for 12 weeks.
- Of the 351 participants, 217 (61.8%) had a sustained initial treatment benefit – with 112 of these then assigned to the placebo and 105 to pimavanserin.
- This shows that pimvanserin more than halved the relapse rate and significantly improved the sustained benefit.