Delayed second Pfizer COVID-19 shot produces more antibodies: Study

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Sumary of Delayed second Pfizer COVID-19 shot produces more antibodies: Study:

  • Pfizer’s COVID-19 vaccine generates antibody responses three-and-a-half times larger in older people when a second dose is delayed to 12 weeks after the first, a British study said..
  • The study released on Friday is the first to directly compare immune responses of the Pfizer shot from the three-week dosing interval tested in clinical trials, and the extended 12-week interval that British officials recommend in order to give more vulnerable people at least some protection quickly..
  • After Britain moved to extend the interval between doses, Pfizer and vaccine partner BioNTech said there was no data to back up the move..
  • “Our study demonstrates that peak antibody responses after the second Pfizer vaccine are markedly enhanced in older people when this is delayed to 12 weeks,”.
  • Britain began rolling out Pfizer’s vaccine before changing dosing policy, meaning a small number of people who got the shot early received the second shot three weeks later..
  • The study, which has not yet been peer-reviewed, looked at 175 people aged between 80 and 99, and found that extending the second dose interval to 12 weeks increased the peak antibody response 3.5-fold compared to those who had it at three weeks….

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