Sumary of Fighting fungal infections with metals:
- While more and more fungal strains are being detected that are resistant to one or more of the available drugs, the development of new drugs has come to a virtual standstill in recent years.
- The researchers observed that just one of the eleven tested metal compounds showed signs of toxicity, while the others were well tolerated by the larvae.
- In the next stride, some metal compounds were tested in an infection version, and one compound was effective in reducing the fungal infection in larvae.
- However, Frei, who is trying to develop new metal-based antibiotics with his research faction at the University of Bern, has found that over 1,000 of the more than 300,000 compounds tested by CO-ADD contained metals.