High-dose edoxaban safety favorability vs. warfarin greater in women than men

February 23, 2021

3 min read


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Disclosures: Giugliano reports he received research support from Amgen, Anthos Therapeutics, Daiichi Sankyo; honoraria for CME lectures from Amgen, Daiichi Sankyo, Merck; and consultant fees from Amarin, American College of Cardiology, Amgen, AstraZeneca, Boehringer Ingelheim, Bristol Myers-Squibb, CryoLife, CVS Caremark, Daiichi Sankyo, Eli Lilly, Esperion, Gilead, GlaxoSmithKline, Janssen, Lexicon, Merck, Pfizer, SAJA Pharmaceuticals, Samsung and Servier. Please see the study for all other authors’ relevant financial disclosures.


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Among women with atrial fibrillation at elevated CV risk, treatment with high-dose edoxaban vs. warfarin conferred greater reduction in hemorrhagic stroke and major bleeding compared with men, with similar efficacy, researchers reported…

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