Sumary of ‘Laughing Gas’ May Help Tough-to-Treat Depression:
- By Alan Mozes HealthDay Reporter THURSDAY, June 10, 2021 (HealthDay News) — When antidepressants fail to rein in hard-to-treat depression, the common anesthetic most know as “laughing gas”.
- But following three one-hour laughing gas inhalation sessions spread across three months, 85% of patients had significant depression relief that endured weeks post-treatment..
- “And we found that laughing gas, at a much lower concentration than is used, for instance, during dental procedures, can help patients with difficult-to-treat depression,”.
- And patients exposed to the higher dose commonly experienced side effects, including nausea, sedation and or “mild dissociation,”.
- About one-third were exposed to three sessions of 50% nitrous oxide inhalation treatment, one-third were given a 25% nitrous oxide inhalation treatment and one-third were given an oxygen inhalation treatment that contained no laughing gas..
- After four patients withdrew from the study, results were drawn from 20 patients who completed all three inhalation sessions and four patients who completed at least one treatment..
- Perhaps just as importantly, the team also found that “using a lower concentration of nitrous oxide also reduced the risk of side effects fourfold.”.
- “The mechanism of how nitrous oxide exerts antidepressant effects is unknown, and is likely different from how it induces sedation and unconsciousness and also pain relief,”…