Sumary of Nearly one in five patients who die from unexplained sudden cardiac death have suspicious gene, study finds:
- Researchers from the University of Maryland School of Medicine (UMSOM) and their colleagues found that nearly 20 percent of patients with unexplained sudden cardiac death — most of whom were under age 50 — carried rare genetic variants..
- In some cases, their deaths may have been prevented if their doctors had known about their genetic predisposition to heart disease..
- “Genetic screening isn’t routinely used in cardiology, and far too many patients still die suddenly from a heart condition without having any previously established risk factors..
- To conduct the study, Dr. Finn and his colleagues performed genetic sequencing in 413 patients, who died at age 41 on average of sudden unexplained heart failure..
- The study found that 18 percent of patients who experienced sudden death had previously undetected genes associated with life-threatening arrhythmia or heart failure conditions..
- “Should we be doing routine genetic screening in those who have a family history of unexplained sudden cardiac death?”.
- There are currently no clear guidelines on how to monitor or treat patients with these variants in the absence of clinically detectable disease….