Nearly one in five patients who die from unexplained sudden cardiac death have suspicious gene, stud …

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Sumary of Nearly one in five patients who die from unexplained sudden cardiac death have suspicious gene, study finds:

  • Researchers from the University of Maryland School of Medicine (UMSOM) and their colleagues found that nearly 20 percent of patients with unexplained sudden cardiac death — most of whom were under age 50 — carried rare genetic variants..
  • In some cases, their deaths may have been prevented if their doctors had known about their genetic predisposition to heart disease..
  • “Genetic screening isn’t routinely used in cardiology, and far too many patients still die suddenly from a heart condition without having any previously established risk factors..
  • To conduct the study, Dr. Finn and his colleagues performed genetic sequencing in 413 patients, who died at age 41 on average of sudden unexplained heart failure..
  • The study found that 18 percent of patients who experienced sudden death had previously undetected genes associated with life-threatening arrhythmia or heart failure conditions..
  • “Should we be doing routine genetic screening in those who have a family history of unexplained sudden cardiac death?”.
  • There are currently no clear guidelines on how to monitor or treat patients with these variants in the absence of clinically detectable disease….

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