New adaptable nanoparticle platform enables enhanced delivery of gene therapies

556375

Sumary of New adaptable nanoparticle platform enables enhanced delivery of gene therapies:

  • Scientists have developed polypeptide-based materials that act as effective vectors for delivering gene therapies..
  • The work, led by researchers from RCSI University of Medicine and Health Sciences and funded by Science Foundation Ireland, is published in Biomaterials Science..
  • The success of the COVID vaccines has established nanoparticles as key to the development of many advanced therapies..
  • The researchers developed a platform that produces bespoke star-shaped polypeptide nanoparticles, which effectively deliver a range of therapies, including gene therapies..
  • They placed these nanomedicines in a scaffold that could be implanted into a defect site and deliver the genetic cargo into infiltrating host cells..
  • The gene-loaded scaffold accelerated bone tissue regeneration, with a six-fold increase in new bone formation compared to a scaffold alone..
  • We have shown that these nanoparticles have real potential to be a game changer in the delivery of gene therapies,”.
  • “While more testing is needed before these therapies can be used clinically, our platform allows us to design our polypeptides to meet a variety of delivery scenarios and provide tailored solutions to gene delivery challenges,”…

Want to know more click here go to source.

From -
Close
Generic selectors
Exact matches only
Search in title
Search in content

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close