Patient-reported outcome measure for fatigue may help predict opioid use after THA, TKA

patient reported outcome measure for fatigue may help predict opioid use after tha tka

Sumary of Patient-reported outcome measure for fatigue may help predict opioid use after THA, TKA:

  • November 17, 2021 1 min read Source/Disclosures Published by: Source: Krell EC, et al.
  • Back to Healio The fatigue domain of the 29-item Patient-Reported Outcomes Measurement Information System Profile, or PROMIS-29, used before total hip or knee arthroplasty predicted postoperative opioid use, results of a prospective study showed.
  • “Patients reporting fatigue preoperatively may have greater opioid use postoperatively that can be expected,” Debbi said.
  • Researchers then used statistical models to determine whether any associations existed between total MMEs, refilled MMEs, the PROMIS-29 domains and the time to opioid cessation.
  • According to the abstract, multivariable regression showed an association between each minimal possible increase in the preoperative PROMIS-29 fatigue T-Score and the postoperative consumption of 12 added total MMEs in the first 12 postoperative weeks.
  • In addition, results showed minimal possible increases in the preoperative PROMIS-29 fatigue T-Score were each associated with 18 hours later time to cessation, which was a statistically significant association.
  • “Future studies are needed to further understand the association between fatigue, pain and opioid consumption,” Debbi said.

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