Sumary of Scientists develop a new vaccine approach for HIV:
- Any solution would require coaxing the body into producing a special type of antibody that can act broadly to defeat multiple strains of the virus at once..
- This week, scientists at Scripps Research moved closer to attaining that holy grail of HIV research with a new vaccine approach that would rely on genetically engineered immune cells from the patient’s body..
- In experiments involving mice, the approach successfully induced broadly neutralizing antibodies–also called bnabs–that can prevent HIV infection, says principal investigator James Voss, PhD, of Scripps Research..
- Related Stories Voss and his team showed in 2019 that it was possible to reprogram the antibody genes of the immune system’s B cells using CRISPR so the cells would produce the same broadly neutralizing HIV antibodies that have been found in rare HIV patients..
- He hopes that his vaccine approach may someday prevent new HIV infections and possibly offer a functional cure to those who already have HIV/AIDS….