Seizure patterns in focal epilepsy include high rates of circannual, multidien cycles


February 23, 2021

2 min read


Disclosures: Leguia reports no relevant financial disclosures. Please see the study for all other authors’ relevant financial disclosures.


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A retrospective cohort study of more than 200 patients with medically refractory focal epilepsy that examined seizure patterns identified a “high prevalence” of plural seizure cycles, including multidien and circadian cycles.

The researchers published the study findings in JAMA Neurology.

“Focal epilepsy is characterized by the cyclical recurrence of seizures, but, to our knowledge, the prevalence and patterns of seizure cycles are unknown,” Marc G. Leguia, PhD, of the University of Bern in Switzerland, and colleagues wrote. “In the last decade, the availability of continuous electroencephalography (cEEG) provided a unique opportunity to study seizure cycles at long timescales with objective data and suitable statistics…

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