Some Blood Pressure Meds Raise Heart Risks in People With HIV


Sumary of Some Blood Pressure Meds Raise Heart Risks in People With HIV:

  • TUESDAY, April 6, 2021 — Beta-blocker blood pressure medications may increase the risk of heart problems in people with HIV, new research suggests..
  • Roughly eight in 10 were on one type of blood pressure drug, with 13% on beta-blockers, 11% on calcium channel blockers, 24% on angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers (ACEi/ARBs) and 23% on thiazide or similar diuretics..
  • Among those who had not been diagnosed with heart disease at the beginning of the study, the risk of developing heart disease, heart failure or stroke for the first time was 90% higher among those taking beta-blockers than those taking ACEi/ARBs, the most frequently prescribed type of high blood pressure medication..
  • “We suspected there could be differences in risk based on which medications providers select to treat hypertension among people with HIV due to potential interactions between blood pressure medications and some therapies used to treat the virus,”.
  • “Additionally, factors such as how the body handles salt, inflammation and the accelerated aging of blood vessels may affect the risk of cardiac events in people with HIV differently than people who do not have HIV, which could be influenced by which blood pressure medication is used,”.
  • The increased risk associated with beta-blockers was found whether or not patients had their blood pressure under control..
  • Thiazide or similar diuretics and calcium channel blockers weren’t associated with an increased risk of heart problems, the findings showed..
  • Among veterans with HIV who did not have chronic kidney disease, the use of ACEi/ARBs was associated with a lower risk of developing heart failure, while those taking other blood pressure medications had about a 50% higher risk of heart failure, according to the study…

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