Sumary of UC San Diego receives $12.25 million NIH grant to improve epilepsy treatment:
- The National Institutes of Health has awarded a $12.25 million grant to the University of California San Diego to develop and enhance brain-sensing and brain-stimulating platform technologies to enable treatment of drug-resistant epilepsy.
- The project is led by UC San Diego electrical engineering professor Shadi Dayeh who leads the Integrated Electronics and Biointerfaces Laboratory and brings together expertise from all across UC San Diego, including the Jacobs School of Engineering and Health Sciences.
- The nation-wide team includes researchers and longtime collaborators of Dayeh at Massachusetts General Hospital led by Dr. Sydney Cash and Oregon Health &
- Epilepsy, a group of neurological disorders characterized by repeated seizures, affects more than 3.4 million people in the U.S. according to the Centers for Disease Control and Prevention (CDC);
- In these situations, clinicians try to identify the abnormal brain tissue that generates the seizures.
- Surgeons then target this area for surgical removal, or for implantation of an electrical pulse generator that modifies seizure generation.
- Current technologies to identify the specific regions in the brain that trigger epileptic seizures – called epileptic foci – are imprecise.
- Dayeh’s work in brain-computer interfaces began when he realized his lab’s materials science, device, and integration techniques could allow for sensor grids that offer the tantalizing possibility of providing surgeons with a much clearer picture of the spots in the brain likely initiating the seizures.