$40 million multi-year study to examine long-term impacts of COVID-19 and MIS-C

40 million multi year study to examine long term impacts of covid 19 and mis c

Sumary of $40 million multi-year study to examine long-term impacts of COVID-19 and MIS-C:

  • This $40 million multi-year study will provide important information about quality of life and social impact, in addition to a better understanding of the long-term physical impact of the virus, including effects on the heart and lung.
  • Long COVID is a wide range of symptoms that can last or appear weeks or even months after being infected with the virus that causes COVID-19. The study is designed to enroll at least 1,000 children and young adults under 21 years of age who have a confirmed history of symptomatic or asymptomatic SARS-CoV-2 infection or MIS-C.
  • Participants who enroll within 12 weeks of an acute infection will attend study visits every three months for the first six months and then every six months for three years.
  • Participants who enroll more than 12 weeks after acute infection will attend study visits every six months for three years.
  • The study will also enroll up to 1,000 household contacts to serve as a control group, and up to 2,000 parents or guardians (one parent per participant) will complete targeted questionnaires.
  • “The large number of patients who will be enrolled in this study should provide us with a truly comprehensive understanding of how the virus may continue to impact some patients long after the infection has subsided,” says Dr. DeBiasi.
  • The study primarily aims to determine incidence and prevalence of, and risk factors for, certain long-term medical conditions among children who have MIS-C or a previous SARS-CoV-2 infection.
  • The study will also evaluate the health-related quality of life and social impacts for participants and establish a biorepository that can be used to study the roles of host genetics, immune response and other possible factors influencing long-term outcomes.

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