Sumary of Novel method for glucagon delivery to help individuals living with Type 1 diabetes:
- Sudden and critical drops in blood sugar can go undetected overnight when the child is asleep, resulting in coma and death — an event known as “dead in bed syndrome.
- ” A parent can check their child’s glucose levels right before they go to bed and everything looks fine, then around 2 a.
- their blood sugar is dangerously low — near comatose level.
- In severe situations, glucagon injections can stabilize blood glucose levels long enough for parents to get their child medical attention.
- In the research, Webber and his team illustrate how they successfully developed hydrogels that remain intact in the presence of glucose but slowly destabilize as levels drop, releasing glucagon into the system, raising glucose levels.
- “In the field of glucose-responsive materials, the focus has typically been on managing insulin delivery to control spikes in blood sugar,” Webber said.
- You don’t want your blood sugar to be too high and you don’t want it to be too low.
- We’ve essentially engineered a control cycle using a hydrogel that breaks down when glucose levels drop to release glucagon as needed.