Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19

urinary sars cov 2 rna is a prognosticator of covid 19

Sumary of Urinary SARS-CoV-2 RNA is a prognosticator of COVID-19:

  • It is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which belongs to the betacoronavirus cluster comprising seven members, including SARS and the Middle East respiratory syndrome (MERS).
  • Methods used to screen and diagnose SARS-CoV-2 infection include detecting SARS-CoV-2 nucleic acid, SARS-CoV-2-specific antibody, and antigen.
  • Antigen-based diagnostic tests are less sensitive than reverse transcription-polymerase chain reaction (RT-PCR) -based tests, but they are faster and more convenient alternatives.
  • The positive rates of SARS-CoV-2 nucleic acid in different body fluids are variable, indicating a distinct pattern of persistence and clearance of viral RNA in body fluids of COVID-19 patients.
  • Furthermore, the positive rates detected in extra-pulmonary specimens are usually lower than those seen in nasopharyngeal swabs.
  • It was also found that under certain specific conditions, SARS-CoV-2 might infiltrate from the bloodstream to the kidney parenchyma and may eventually result in renal injury and the urinary shedding of viruses.
  • Acute kidney injury (AKI) is a common complication among hospitalized patients with severe COVID-19 symptoms despite a low urinary virus RNA positive rate among COVID-19 patients.
  • Based on the results, the patients were divided into two groups – the urinary SARS-CoV-2 negative group (URNA−, 38 cases) and the positive group (URNA+, 15 cases).

Want to know more click here go to source.

From -


Site Language

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.