Sumary of Antibiotics may be the new weapon to fight against melanoma:
- Some antibiotics appear to be effective against a form of skin cancer known as melanoma.
- Researchers at KU Leuven, Belgium, examined the effect of these antibiotics on patient-derived tumors in mice.
- Researchers from KU Leuven may have found a new weapon in the fight against melanoma: antibiotics that target the ‘power plants’ of cancer cells.
- These antibiotics exploit a vulnerability that arises in tumor cells when they try to survive cancer therapy.
- As the cancer evolves, some melanoma cells may escape the treatment and stop proliferating to ‘hide’ from the immune system.
- These are the cells that have the potential to form a new tumor mass at a later stage.
- In order to survive the cancer treatment however, those inactive cells need to keep their ‘power plants’ – the mitochondria – switched on at all times”.
- As mitochondria derive from bacteria that, over time, started living inside cells, they are very vulnerable to a specific class of antibiotics.