Shape-shifting fat cells fuel breast cancer growth

Sumary of Shape-shifting fat cells fuel breast cancer growth:

  • When the researchers enhanced the lipid-storing capacity of mature fat cells, they ceased to morph into other cell types and no longer promoted tumor growth.
  • Simmons Comprehensive Cancer Center to better understand the connection between cancer risk and obesity.
  • However, this property also depended critically on their ability to supply energy to neighboring tumor cells.
  • We identified novel adipocyte-derived cell types in the mammary gland that offer a fertile soil for breast cancer tumor invasion and growth, said study leader Philipp Scherer, Ph.D., Professor of Internal Medicine and Cell Biology and a member of the Harold C.

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