Kidney donation may increase hypertension risk but shows no link to cardiovascular disease

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Sumary of Kidney donation may increase hypertension risk but shows no link to cardiovascular disease:

  • “Kidney donors are carefully selected, inherently healthy and often also biological and/or socially related to patients with kidney disease and thus, identifying a relevant comparison group remains a major challenge in observational studies,”.
  • “Consequently, the results of such studies might be confounded by a greater baseline risk of CVD in the comparison cohort leading to an underestimation of the relative risk in kidney donors.”.
  • with kidney donors having a decreased risk for AF, MACE and all-cause mortality (hazard ratios [HRs] of 1.11, 0.59, 0.68 and 0.57, respectively)..
  • Comparisons between kidney donors and blood donors showed that while kidney donors had an increased risk of initiating treatment for hypertension (standardized incidence ratio [SIR] = 1.40), they did not have an increased risk for MACE, AF or morality (SIRs of 1.17, 0.88 and 1.10, respectively)…

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