No link between moderate coffee consumption and increased risk of cardiac arrhythmia, researchers fi …

no link between moderate coffee consumption and increased risk of cardiac arrhythmia researchers find

Sumary of No link between moderate coffee consumption and increased risk of cardiac arrhythmia, researchers find:

  • “Coffee is the primary source of caffeine for most people, and it has a reputation for causing or exacerbating arrhythmias,” said senior and corresponding author Gregory Marcus, MD, professor of medicine in the Division of Cardiology at UCSF.
  • “But we found no evidence that caffeine consumption leads to a greater risk of arrhythmias,” said Marcus, who specializes in the treatment of arrhythmias.
  • “Our population-based study provides reassurance that common prohibitions against caffeine to reduce arrhythmia risk are likely unwarranted.
  • ” While some professional societies suggest avoiding caffeinated products to lower the risk for arrhythmia, this connection has not been consistently demonstrated — indeed, coffee consumption may have anti-inflammatory benefits and is associated with reduced risks of some illnesses including cancer, diabetes, and Parkinson disease.
  • In the new study, UCSF scientists explored whether habitual coffee intake was associated with a risk of arrhythmia, and whether genetic variants that affect caffeine metabolism could modify that association.
  • Their investigation was conducted via the community-based UK Biobank, a prospective study of participants in England’s National Health Services.
  • As those with the genetic variants associated with faster caffeine metabolism drank more coffee, this analysis provided a method to test the caffeine-arrhythmia relationship in a way that did not rely on participant self-report and should have been immune to much of the confounding inherent to most observational studies.
  • No evidence of a heightened risk of arrhythmias was observed among those genetically predisposed to metabolize caffeine differently.

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