Sumary of Pro-inflammatory diets may increase breast cancer risk:
- Inflammatory potential of the diet and risk of breast cancer in the European Investigation Into Cancer and Nutrition (EPIC) study..
- of carcinogenesis, and previous research has demonstrated an association between low-grade chronic inflammation and several cancers, according to Carlota Castro-Espin, BSc, MS, a PhD student from the Catalan Institute of Oncology at Hospitalet de Llobregat in Catalonia, Spain..
- “The impact of inflammation on breast cancer risk is often assumed to have an indirect effect, mainly mediated through obesity and decreased physical activity.”.
- Although diet contributes to low-grade chronic inflammation, no dietary components other than alcohol have been linked to breast cancer “with a convincing degree of evidence,”.
- Castro-Espin and colleagues analyzed data from the EPIC study to evaluate the inflammatory potential of diets and their impact on breast cancer risk..
- Castro-Espin reported that women with the highest ISD values — indicating the most pro-inflammatory diets — had a 12% increased risk for breast cancer compared with women who had the most anti-inflammatory diets (HR = 1.12;.
- Each standard deviation increase in ISD was associated with a 4% increased risk for breast cancer among all participants..
- The association appeared to be stronger in premenopausal women, who had an 8% increased risk for breast cancer with each standard deviation increase in ISD….