Sumary of Researchers use information theory to monitor resistance mechanisms to targeted cancer therapy:
- In order to overcome this challenge, a team from the University of Geneva (UNIGE) and the University Hospitals of Geneva (HUG), Switzerland, has used information theory for the first time, in order to objectify in vivo the molecular regulations at play in the mechanisms of the adaptive response and their modulation by a therapeutic combination.
- Research confronted with the complexity of biological regulations In order to prevent resistance to targeted therapies, scientists need to understand the molecular mechanisms of the adaptive response.
- Applying information theory to tumors To counter these difficulties, the UNIGE and HUG team came up with the idea of using information theory, more specifically by quantifying mutual information.
- This approach has previously been used in biology, mainly to quantify cell signaling and understand genetic regulation networks.