Sumary of Cannabis ‘not harmless’ given link between overuse, schizophrenia:
- July 22, 2021 2 min read Source/Disclosures Disclosures: The study authors report no relevant financial disclosures.
- Back to Healio The proportion of schizophrenia cases linked to cannabis use disorder increased three- to fourfold in the past 2 decades, according to results of a nationwide prospective cohort study published in JAMA Psychiatry.
- ” According to Hjorthøj and colleagues, the population-attributable risk fraction (PARF), which, for the purposes of this study, was the proportion of cases of schizophrenia considered attributable to cannabis, would reflect an increase if the link between cannabis use and schizophrenia was causal.
- The researchers aimed to assess this potential causality by conducting a nationwide, register-based historical prospective cohort study that included all individuals (n = 7,186,834;
- Results showed the adjusted HR for schizophrenia fluctuated at approximately four during most of the study period when individuals with a cannabis use disorder diagnosis were compared with those without this diagnosis.