Sumary of VIDEO: Increased visceral adipose tissue links to decreased IBD remission:
- Higher visceral adipose tissue is associated with lower rates of steroid-free deep and endoscopic remission in patients starting biologic therapy for inflammatory bowel diseases: results from the constellation study.
- Back to Healio Higher visceral adipose tissue correlated with lower rates of inflammatory bowel disease remission among patients dosed with infliximab, vedolizumab or ustekinumab, according to Andres Yarur, MD, Medical College of Wisconsin.
- ” In a prospective cohort study, researchers aimed to assess the association between baseline visceral adipose tissue (VAT) percentages, as well as other body composition parameters, with biologic response in patients with IBD.
- Study results showed visceral fat mass percentage played a significant role in steroid-free deep remission at week 14 in both univariate analysis (OR = 0.29;
- “The big question here is what can we do to modify future randomized trials looking into interventions and seeing if reducing their VAT percentages influences their response to treatment,” Yarur concluded.