Could an antiviral mouthwash using silver nanoparticles prevent COVID-19?

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Sumary of Could an antiviral mouthwash using silver nanoparticles prevent COVID-19?:

  • People who come in contact with coronavirus disease 2019 (COVID-19) patients are high-risk individuals for becoming infected with its causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)..
  • Viral transmission in hospitals is a particular area of concern, as the close interaction between the healthcare personnel and the patients helps the transmission of the virus – between them, their families and subsequently to their communities..
  • Despite various public health interventions implemented, such as adaptation of areas with negative air pressure, isolation areas for patients with COVID-19, and the mandatory use of personal protective equipment (PPE), controlling SARS-CoV-2’s spread has had mixed results..
  • In the absence of effective antiviral treatments, the ongoing vaccination campaign is the main strategy across the globe to prevent SARS-CoV-2..
  • In a recent study by a team of researchers in Mexico, Russia and Spain, silver nanoparticles (AgNPs) were found to inhibit SARS-CoV-2 in healthcare workers..
  • They propose a non-pharmaceutical public health intervention consisting of mouthwash and nose rinse with an AgNPs solution to reduce morbidity among healthcare personnel exposed to the SARS-CoV-2 virus..
  • The researchers demonstrated clinical evidence to confirm the prevention of SARS-CoV-2 infection in health personnel who performed mouthwash and nose rinse solution with AgNPs..
  • To our knowledge, this study is the first experimental in vitro and in vivo trial where AgNPs as mouthwash and nasal rinse solution are applied for SARS-CoV-2 contagion prevention,”.
  • The study, published on the preprint medRxiv* server, tested a mouthwash ARGOVIT® AgNPs which contains AgNPs and evaluated for prevention of SARS-CoV-2 infection in health workers..
  • control) to evaluate the efficacy of the mouthwash and nasal rinse with AgNPs solution for preventing SARS-CoV-2 infection in the health personnel at the General Tijuana Hospital in Mexico..
  • Using logistic regression, the strong relationship between the fact of mouthwashes and nose rinse in the health personnel and the mitigation of the SARS-CoV-2 contagion with an efficiency of 84.8% is proved.”.
  • Significantly, the study also showed no harmful side effects in the participants who used AgNPs as a mouthwash and nasal rinse for 9 weeks..
  • The researchers observed that the incidence of SARS-CoV-2 infection significantly reduced in the “experimental”.
  • This calculated to an efficiency of 84.8%, suggesting that the mouthwash could be an effective use of AgNPs in preventing SARS-CoV-2 infection…

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