Sumary of COVID-19 vaccination in New York City reduces hospital admissions and deaths:
- Since the emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, millions of lives have been lost, and ten times that number of patients have required hospitalization to successfully overcome the infection.
- A new study, released as a preprint on the medRxiv* server, shows how the successful rollout of effective COVID-19 vaccines in this metropolis led to the dramatic reduction in the number of cases with moderate to severe coronavirus disease 2019 (COVID-19) and curbed related-COVID-19 mortality.
- The unprecedented speed with which the earliest vaccines were developed and presented for emergency use authorizations led to the first vaccination shot in NYC being administered as early as December 2020. By July 2021, almost 70% of adults living in the city have received at least one dose of a COVID-19 vaccine.
- Reduced severe and fatal outcomes The current study is a pioneering attempt to provide a formal evaluation of the effect of vaccination on COVID-19 hospitalizations and mortality.
- Incorporating the demographic, age-dependent odds of adverse outcomes, contact patterns and the known natural history of the infection, the scientists modeled a priming-booster dose vaccine regimen with age-dependent prioritization following real-life criteria.
- The resulting vaccine allocation and administration mimicked the actual NYC performance.
- Related StoriesThe increased efficacy of the vaccine against symptomatic COVID-19 was expected to bring about precisely this outcome, with the reduction in deaths and severe symptoms being more marked than the drop in the number of cases.
- symptomatic/severe illness reduction, since these groups were at unduly high risk for severe or critical COVID-19. The alpha variant rapidly rose to dominance first in the UK and then throughout the world.