Sumary of Pfizer shot generates most COVID-fighting antibodies: Comparative study:
- Pfizer Inc. and BioNTech SE’s COVID-19 shot yielded the strongest immune response among four vaccines tested in a study, which found people getting Sinopharm’s inoculation may be particularly susceptible to a breakthrough coronavirus infection.
- Levels of protective antibodies to the part of the coronavirus that SARS-CoV-2 uses to infect human cells varied widely across each of the four vaccine groups.
- They are likely to include factors such as the amount of active ingredient in each dose and the interval between getting the first and second shots, said the authors from Stanford University, the Onom Foundation, and the National Center for Zoonotic Diseases in Ulaanbaatar in the paper published Thursday.
- The study was conducted in July among 196 fully-immunized people in Mongolia, where all four shots were used, a rarity.
- The results suggested that Sinopharm recipients, who accounted for 89.2 percent of vaccinated adults in Mongolia at the time, as well as the smaller number of people given Sputnik V or AstraZeneca vaccines, could be susceptible to breakthrough infections, the authors said.
- Booster shots “Additional public health interventions, such as booster vaccine doses, potentially with the more potent vaccine types, may be needed to further control the COVID-19 pandemic in Mongolia and worldwide, they said.