Researchers develop “cell encapsulation” technology to stimulate immunity to fight cancer

92941

Sumary of Researchers develop “cell encapsulation” technology to stimulate immunity to fight cancer:

  • Immunotherapy techniques developed in oncology to combat cancerous cells have great potential for fighting viruses..
  • A research team from the University Hospitals of Geneva (HUG) and the University of Geneva (UNIGE), in Switzerland, in collaboration with MaxiVAX, a spinoff of both institutions, developed an innovative technology called “cell encapsulation”..
  • Originally designed to stimulate immunity to fight cancer, the COVID-19 pandemic motivated the scientists to broaden the scope of their technology to test its effectiveness against viruses..
  • The immune system is able to identify cancer cells and fight them, just as it does against a viral or bacterial pathogen..
  • To this end, Nicolas Mach and his team, in partnership with the company MaxiVAX, developed a novel cell-based cancer vaccination using cell encapsulation technology..
  • Exciting the immune system over the long term Cell encapsulation consists of filling a semipermeable capsule with engineered cells before implanting it subcutaneously..
  • This technology therefore allows the stable and sustained long-term production and release of proteins such as cytokines or antibodies..
  • Loaded with cells modified to secrete a substance capable of stimulating the immune system, the capsule can be used as an adjuvant cargo ship..
  • To efficiently boost the immune system, the scientists used the tool they developed over the last two years, a genetically modified muscle cell line secreting GM-CSF, a protein known to promote the growth of white blood cells and able, under certain conditions, to train very effectively the immune system to react against a pathogenic target..
  • “GM-CSF is like a hormone for the white blood cells, which are just as useful for defeating tumours as they are for defeating pathogens,”.
  • explains the oncologist.In order to use GM-CSF as an adjuvant to enhance the immune response against the SARS-CoV-2 Spike target, the lab-produced cells are encapsulated…

Want to know more click here go to source.

From -

Close

Site Language


By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close