A ‘promising’ treatment for Alzheimer’s has arrived and it could ‘transform& …

a promising treatment for alzheimers has arrived and it could transform lives study

Sumary of A ‘promising’ treatment for Alzheimer’s has arrived and it could ‘transform’ lives – study:

  • New research published today draws attention to a novel approach to potentially treating Alzheimer’s disease – the most common type of dementia characterised by memory loss.
  • Rather than focus on the amyloid beta protein in plaques in the brain, which are commonly associated with Alzheimer’s disease, the antibody and vaccine both target a different soluble form of the protein, which is thought to be highly toxic.
  • Amyloid beta protein naturally exists as highly flexible, string-like molecules in solution, which can join together to form fibres and plaques.
  • Professor Thomas Bayer, from the University Medical Center Göttingen, said: “In clinical trials, none of the potential treatments which dissolve amyloid plaques in the brain have shown much success in terms of reducing Alzheimer’s symptoms.
  • We identified an antibody in mice that would neutralise the truncated forms of soluble amyloid beta, but would not bind either to normal forms of the protein or to the plaques.
  • ”DON’T MISSThe everyday food item potentially causing cancer [INSIGHT]The breakfast drink that’s a ‘hard no’ in the morning [TIPS]Dementia diet: Common food type to eat everyday [TIPS]Doctor Preeti Bakrania and colleagues from LifeArc adapted this antibody so a human immune system wouldn’t recognise it as foreign and would accept it.
  • When the Leicester research group looked at how and where this “humanised” antibody, called TAP01_04, was binding to the truncated form of amyloid beta, the team had a surprise.
  • They saw the amyloid beta protein was folded back on itself, in a hairpin-shaped structure.

Want to know more click here go to source.

From -

Close

Site Language


Popular Posts

1,907

By continuing to use the site, you agree to the use of cookies. more information

The cookie settings on this website are set to "allow cookies" to give you the best browsing experience possible. If you continue to use this website without changing your cookie settings or you click "Accept" below then you are consenting to this.

Close