Diet trumps drugs for anti-aging and good metabolic health

diet trumps drugs for anti aging and good metabolic health

Sumary of Diet trumps drugs for anti-aging and good metabolic health:

  • The pre-clinical study by the University of Sydney’s Charles Perkins Centre suggests the makeup of our diet could be more powerful than drugs in keeping conditions like diabetes, stroke and heart disease at bay.
  • The research builds on the team’s pioneering work in mice and humans demonstrating the protective role of diet and specific combinations of proteins, fats and carbohydrates against ageing, obesity, heart disease, immune dysfunction and risk of metabolic diseases, such as type 2 diabetes.
  • Senior author and Academic Director of the Charles Perkins Centre, Professor Stephen Simpson said drugs can also target the same biochemical pathways as nutrients.
  • “We discovered dietary composition had a far more powerful effect than drugs, which largely dampened responses to diet rather than reshaped them,” said Professor Simpson.
  • “Given humans share essentially the same nutrient-signalling pathways as mice, the research suggests people would get better value from changing their diet to improve metabolic health rather than taking the drugs we studied.
  • ” The study explained The research team designed a complex mouse study, involving 40 different treatments, each with varying levels of protein, fat and carbohydrate balance, calories and drug content.
  • The researchers found calorie intake and the balance of macronutrients (protein, fats and carbohydrates) in the diet had a strong impact on the liver.
  • Protein and total calorie intake had a particularly powerful effect not just on metabolic pathways, but also on fundamental processes that control the way our cells function.

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