Rapamycin changes the way our DNA is stored


Sumary of Rapamycin changes the way our DNA is stored:

  • Our genetic material is stored in our cells in a specific way to make the meter-long DNA molecule fit into the tiny cell nucleus of each body cell..
  • In humans, this DNA molecule is two meters long — yet it fits into the cell nucleus, which is only a few micrometres in size..
  • To study the effect of rapamycin on histone proteins, the researchers analysed various organs of the fruit fly Drosophila melanogaster..
  • In further experiments, Yu-Xuan Lu and his colleagues were able to show that the increased levels of certain histone proteins in a specific gut cell type called enterocytes reduced tumour growth, improved gut health and extended lifespan of the animals…

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